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ARTEMIS (darunavir)

Clinical trial • Reported • 10 May 2007
This trial is concluded. This means the trial has been completed. The results of the trial are summarised in the 'results' section of this page. You cannot enrol in this trial.

About this trial

This study is comparing darunavir boosted with low-dose ritonavir (TMC 114/r) with lopinavir boosted with low-dose ritonavir (Kaletra) in people who have never taken any antiretroviralA medication or other substance which is active against retroviruses such as HIV. treatment before. All people on the study will also be treated using the fixed-dose combination of tenofovir combined with emtricitabine (Truvada).

The two approaches will be compared for safety, tolerability and effectiveness(Of a drug or treatment). The maximum ability of a drug or treatment to produce a result regardless of dosage. A drug passes efficacy trials if it is effective at the dose tested and against the illness for which it is prescribed. In the standard procedure, Phase II clinical trials gauge efficacy, and Phase III trials confirm it. in fighting HIV.

Official title:Trial of an investigational protease inhibitor TMC114 with ritonavir (TMC114/r) in HIV-1 infected patients who have never been treated with antiretroviral medications
What is this trial studying?Existing drug – darunavir
Start date:Sep 2005

This may be the proposed or expected start date for trials which have not yet started.

How long is this trial planned to go for?Participants in this trial will be asked to take the trial drug for 48 weeks. Following the conclusion of the trial, participants will be followed up for a further 96 weeks.
Links to further information:
Related trials:
Can I access this treatment other than by enrolling in this trial?

Darunavir is now a registered drug in Australia available through the PBS[Pharmaceutical Benefits Scheme] The federal government program which subsidises medication costs in Australia. Anti-HIV drugs are part of a special part of the PBS called Section 100 (S100) which is used for expensive, highly specialised drugs..

Who can enrol in this trial?

You may be eligible to participate in this trial if you meet the following criteria:

  • At least 18 years old
  • Have never taken HIV treatments
  • Viral load at least 5000 copies/ml
You will not be eligible to participate in this trial if you meet any of the following criteria:
  • Have taken HIV treatments in the past

This is a summary of key inclusion and exclusion criteria for this trial. There may be other criteria which may exclude some people from participation in this trial. Some laboratory tests may also be required. Consult your doctor, or view the trial protocol or informed consent documentation to see the full range of exclusion and inclusion criteria.

Results:

See link above for 48 week data

Disclaimer

While NAPWA has taken every care to compile the information on this page and to keep it up-to-date, we cannot guarantee its correctness and completeness.

  • Before making the decision to participate in any clinical research, read our background information.
  • Email NAPWA if you have any questions or comments about this trial
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This Clinical trial was first published on 10 May 2007 — more than five years ago.

While the content of this clinical trial was checked for accuracy at the time of publication, NAPWA recommends checking to determine whether the information is the most up-to-date available, especially when making decisions which may affect your health.

This article may contain medical information. NAPWA makes every reasonable effort to ensure the information on this website is accurate, reliable and up-to-date, including obtaining technical reviews by medically-qualified reviewers, however the authors of information on this website are not qualified to give medical advice, except where explicitly stated.

The content of this website is intended to support, not replace, the relationship between people living with HIV/AIDS and their medical advisers, and is not intended as a substitute for medical advice.

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