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Understanding HIV treatments

Having a good level of treatments literacy is a key to living successfully with HIV. Issues such as different drug classesA group of anti-HIV drugs with the same target of action. Anti-HIV drug classes include nucleoside analogue reverse transcriptase inhibitors, protease inhibitors and non-nucleoside analogue reverse transcriptase inhibitors, as well as several others. Combining drugs from three or more classes is the basis of Highly Active Antiretroviral Therapy (HAART)., resistanceHIV which has mutated and is less susceptible to the effects of one or more anti-HIV drugs is said to be resistant., adherance and side effects are covered below.

Key resources

HIV Tests and Treatments 2009

This resource describes the currently available antiviralA medication or substance which is active against one or more viruses. May include anti-HIV drugs, but these are more accurately termed antiretrovirals. drugs for the treatment and management of HIV infection. It also describes some common tests used to monitor the health of people with HIV, and how these tests can be used to help you look after your health, or make decisions about starting, stopping or changing antiviral treatments.

What newbies think about treatment

Positive Living article • David Menadue • 27 November 2011
Treating HIV

We may be moving towards an era when treating HIV earlier becomes the norm, but it appears that many still don’t understand the benefits of treatment; and how far HIV medicine has come. read more »

Abacavir or tenofovir for first-line?

Positive Living article • Graham Stocks • 24 November 2011

According to the Canadian Observational CohortIn epidemiologyThe branch of medical science that deals with the study of incidence and distribution and control of a disease in a population., a group of individuals with some characteristics in common. A cohort study is a special kind of clinical trialA clinical trial is a research study to answer specific questions about vaccines or new therapies or new ways of using known treatments. Clinical trials are used to determine whether new drugs or treatments are both safe and effective. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people. Trials are in four phases: Phase I tests a new drug or treatment in a small group; Phase II expands the study to a larger group of people; Phase III expands the study to an even larger group of people; and Phase IV takes place after the drug or treatment has been licensed and marketed. which looks at a treatment or treatment strategy in a cohort of people. collaboration, abacavir (ABC) or tenofovir (TDF) are equally effective in first-line treatment.

The authors found that in their group of treatment-naive patients starting treatment, there was no difference in time to suppression with ABC/3TC (Kivexa) versus TDF/FTC (Truvada). read more »

Questioning online health information

Positive Living article • Adrian Ogier • 3 March 2011

With around 80% of Australians claiming that they search online for health information, the NPS has developed five questions you should ask to help you decide if the medical or health information you find on the internet is accurate, unbiased and up to date. read more »

PLHIV more adherent than average Australians

Positive Living article • Adrian Ogier • 25 February 2011

New findings from a survey conducted by the National Prescribing Service (NPS) have shed some light on how Australians are using and misusing medicines. read more »

Once-daily raltegravir not as effective

Positive Living article • Adrian Ogier • 25 February 2011

Merck has terminated a trial comparing once-daily dosing against the currently recommended twice-daily dosing of raltegravir. read more »

Snippets from ASHM

Positive Living article • Adrian Ogier • 2 December 2010

The Australasian HIV/AIDS Conference was held in Sydney in October. Here are some of the treatment highlights: read more »

Triple class resistant strain

Positive Living article • Adrian Ogier • 2 December 2010

Doctors at St Vincent’s Hospital in Sydney have reported two cases of transmitted triple-class drug resistantHIV which has mutated and is less susceptible to the effects of one or more anti-HIV drugs is said to be resistant. HIV.

The first case was diagnosed in 2006 and they believe this person passed the same strain[HIV strain] Any subgroup of the HIV species. Because HIV mutates very easily, there are many different strains (and may be multiple strains within a single person). onto the second case which was identified in 2008. read more »

Raltegravir approved for first line

Positive Living article • Adrian Ogier • 3 September 2010

The Pharmaceutical Benefits Scheme[Pharmaceutical Benefits Scheme] The federal government program which subsidises medication costs in Australia. Anti-HIV drugs are part of a special part of the PBS called Section 100 (S100) which is used for expensive, highly specialised drugs. (PBS) has broadened access to raltegravir (Isentress) beyond treatment-experienced adults.

Raltegravir is now also available for people who are first starting HIV treatment.

Raltegravir + Truvada is now one of four preferred commencing regimens in the Australian HIV Treatment Guidelines. read more »

Commitment to people living with HIV and best health outcomes: Gilead

Media release • 9 August 2010

Last week NAPWA raised concerns related to a recent advertising campaign initiated by Gilead Australia, running in print and radio media. Through discussion Gilead have agreed to consult more widely on future patient based initiatives, and end the current advertising campaign earlier than planned. read more »

‘Live a Little Simpler’ ads a little too simplistic

Media release • 5 August 2010

A pharmaceutical company advertising campaign will create confusion about HIV treatment choices and risks complicating the doctor-patient relationship, the National Association of People Living with HIV/AIDS (NAPWA) has said. read more »

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HIV Clinical Trials update

Recently updated entries from the NAPWA Clinical Trials database.