New data about IDX899, an experimental next generation NNRTI, was presented at the International AIDS Conference, showing reduced viral load in test tube studies both in wild-type HIV and strains with NNRTI-resistance mutations.
Experimental treatments
Rilpivirine (TMC-278)
From the September 2008 issue of Positive Living
Follow-up results from a Phase II study of rilpivirine (TMC-278), Tibotec’s experimental next generation NNRTI, indicate that when combined with Truvada or Combivir, rilpivirine has comparable results to the leading NNRTI, efavirenz.
New NNRTI shows early results
From the September 2008 issue of Positive Living
An experimental NNRTI, RDEA806, appeared to have strong antiviral activity and a favourable safety profile in a Phase II study presented at IAS 2008.
AIDS 2008: Is the HIV drug pipeline drying up?
From the September 2008 issue of Positive Living
The International AIDS Conference heard promising reports about the newer HIV treatments designed to help treat people with advanced and drug-resistant HIV, all of which are now available in Australia.
Etravirine promising for those with NNRTI resistance
From the July 2008 issue of Positive Living
An encouraging outcome of the DUET studies is that etravirine is effective against HIV mutations resistant to existing NNRTIs, efavirenz and nevirapine.
Darunavir and the risk of hepatitis
From the July 2008 issue of Positive Living
A warning has been issued by Tibotec, the manufacturers of Prezista (darunavir) regarding the risk of developing drug- induced hepatitis while taking the treatment.
Good news, bad news: report from CROI
From the March 2008 issue of Positive Living
John Daye, NAPWA's Health, Treatments & Research Portfolio Co-Convenor reports from the 15th Conference on Retroviruses and Opportunistic Infections (CROI) held in Boston, USA from 3-6 February 2008
IAS 2007: Promising signs
From the October 2007 issue of Positive Living
A major HIV/AIDS medical conference in Sydney has generated lots of news on the treatments front, reports Paul Kidd.
CROI 2007: A great leap forward
From the March 2007 issue of Positive Living
A major scientific conference on HIV has wound up with promising news on treatments which could signal a significant improvement in HIV treatment for the first time in some years.
News and treatments briefs
From the March 2007 issue of Positive Living
HIV-related news in brief from the March 2007 edition of Positive Living.