Side effects may be difficult to manage at first but some of them are really time- limited and disappear after a period of several weeks or up to two months. Because the first two weeks on a new treatment are the most difficult, you might consider planning to take time off work or organising childcare. Talk to your doctor in detail about what to expect and which side effects are known to settle, and which side effects tend to be ongoing.
Some side effects may occur because your combination therapy [1]Highly Active AntiRetroviral Therapy ??? aggressive treatment of HIV infection using several different drugs together. is interacting with other drugs you are taking. Make sure that you have told your HIV doctor about all the other drugs you use, including vitamin and herbal supplements and recreational drugs.
Links:
[1] http://www.napwa.org.au/glossary/term/96
[2] http://www.napwa.org.au/resource/treat-yourself-right/some-common-side-effects-and-how-to-manage-them
[3] http://www.napwa.org.au/resource/treat-yourself-right/making-decisions-about-treatment/side-effects
[4] http://www.napwa.org.au/resource/treat-yourself-right/lipodystrophy-changes-in-body-shape