NAPWA

An independent committee, composed of community representatives and clinicalPertaining to or founded on observation and treatment of participants, as distinguished from theoretical or basic science. research experts, that reviews data while a clinical trialA clinical trial is a research study to answer specific questions about vaccines or new therapies or new ways of using known treatments. Clinical trials are used to determine whether new drugs or treatments are both safe and effective. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people. Trials are in four phases: Phase I tests a new drug or treatment in a small group; Phase II expands the study to a larger group of people; Phase III expands the study to an even larger group of people; and Phase IV takes place after the drug or treatment has been licensed and marketed. is in progress to ensure that participants are not exposed to undue risk. A DSMBAn independent committee, composed of community representatives and clinical research experts, that reviews data while a clinical trial is in progress to ensure that participants are not exposed to undue risk. A DSMB may recommend that a trial be stopped if there are safety concerns or if the trial objectives have been achieved. may recommend that a trial be stopped if there are safety concerns or if the trial objectives have been achieved.