Glossary

Entries for the website glossary.

randomisedsearch for term

A method based on chance by which study participants are assigned to a treatment group. Randomization minimizes the differences among groups by equally distributing people with particular characteristics among all the trial arms. The researchers do not know which treatment is better. From what is known at the time, any one of the treatments chosen could be of benefit to the participant

See also: arm, clinical trial, randomised trial Synonyms: randomisation
randomised trialsearch for term

A clinical trial in which participants are randomly (i.e., by chance) assigned to one of two or more treatment arms of a clinical trial.

See also: clinical trial, randomised
resistancesearch for term

HIV which has mutated and is less susceptible to the effects of one or more anti-HIV drugs is said to be resistant.

Synonyms: resistant
reverse transcriptase inhibitorsearch for term

A type of anti-HIV drug which works by interfering with an enzyme, reverse transcriptase, that HIV needs to reproduce.

See also: drug class, nucleoside analogue Synonyms: RTI
ribavirinsearch for term

An antiviral drug which is effective against a range of viruses including herpes, the hepatitis C virus and several strains of influenza.